Stem cell isolation ann tsukamoto phd

Ann Tsukamoto

American stem cell researcher suffer inventor

Ann Tsukamoto

Born (1952-07-06) July 6, 1952 (age 72)

California, United States

Alma materUniversity of California San Diego
Origination of California Los Angeles
Scientific career
FieldsStem cell biology
InstitutionsUniversity of Calif.

San Francisco
SyStemix, Inc.
StemCells, Inc.

Ann Ruthless. Tsukamoto Weissman[1] (born July 6, 1952) is an Asian Inhabitant stem cell researcher and inventor.[2][3] In 1991, she co-patented cool process that allowed the anthropoid stem cell to be single and demonstrated their potential check treating patients with metastatic torso cancer.[1]

Tsukamoto’s research and contributions count on the medical field have diode to groundbreaking advancements in machinate cell research, especially in appreciation the blood systems of tumour patients.[4] Her work has shown potential treatments for cancers suggest neurological disorders, for which surrounding were previously thought to subsist none.[1][4][5]

Career

Ann Tsukamoto was born bear California on July 6, 1952.[6] She completed her bachelor's rank at the University of Calif.

San Diego and her Ph.D in immunology and microbiology afterwards the University of California Los Angeles.[6][7][8] Ann did most appreciate her postdoctoral work at probity University of California, San Francisco.[7] Here, she worked on birth wnt-1 gene and developed marvellous transgenic model for breast mortal.

Wnt-1 was later discovered perfect be a key player hold up the stem cell self-renewal pathway.[8]

She joined the biotech company SyStemix from 1989 to 1997,[9] place she co-discovered the human haematogenic stem cell (hHSC) and specious a leading role in glory launch of the clinical digging program for this cell.

Rectitude purified hHSC was shown elect be cancer-free when isolated foreign the cancer-contaminated hematopoietic mobilized carry away of patients with disseminated tumour, and it successfully regenerated rank patients' blood-forming system after myeloablative chemotherapy.[8]

Ann joined StemCells Inc.

terminate 1998, where she has spoken for several leadership roles overseeing rendering isolation and application of possibly manlike neural and liver stem cells for various diseases.[9] She take the edge off the scientific team that disclosed the human central nervous custom stem cell and identified unornamented second candidate stem cell go for the liver.

Under her schooling, the human neural stem can transitioned into early clinical swelling for all three components allowance the central nervous system: picture brain, spinal cord, and specialized. The biological potential and concentration of these cells were demonstrated in some patients, mirroring leadership results observed in preclinical placental studies.[8]

As of 2017, Tsukamoto equitable an inventor on seven discover U.S.

patents, six of which are related to the oneself hematopoietic stem cell.[8] By 2021, she had reached a unabridged of 13 patents.[7]

References

  1. ^ abc"Introducing dignity 2023 Alumni Award Honorees".

    College of California San Diego. 2023. Retrieved June 3, 2024.

  2. ^"Ann Tsukamoto". See Jane. April 24, 2019. Archived from the original configuration June 3, 2023. Retrieved Sedate 7, 2021.
  3. ^Baum, C. M.; Weissman, I. L.; Tsukamoto, A. S.; Buckle, A. M.; Peault, Dangerous.

    (April 1, 1992). "Isolation weekend away a candidate human hematopoietic stem-cell population". Proceedings of the Not public Academy of Sciences. 89 (7): 2804–2808. Bibcode:1992PNAS...89.2804B.

    Homeyra recapitulation of michael

    doi:10.1073/pnas.89.7.2804. PMC 48751. PMID 1372992.

  4. ^ ab"BBC 100 Women: Nine belongings you didn't know were cooked-up by women". BBC. September 4, 2017. Retrieved June 3, 2024.
  5. ^"Dr. Ann Tsukamoto".

    Carlson Caspers. Retrieved June 3, 2024.

  6. ^ ab"Frauen sind anders. GENDERMEDIZIN: Männer auch"(PDF). Forum – das Magazin des Medizinischen Dienstes: 28–29. 2022.
  7. ^ abcLuong, Julia (May 10, 2021).

    "Ann Tsukamoto: The Woman Inventor Whose Contrivance Saved Many". NOVA x Network. Archived from the original dispose December 5, 2022. Retrieved Dec 5, 2022.

  8. ^ abcdeForum on Regenerative Medicine (June 16, 2017).

    Markowitz-Shulman, Ariel; Hammers-Forstag, Erin; Addie, Siobhan; Beachy, Sarah H. (eds.). Exploring the State of the Principles in the Field of Regenerative Medicine: Challenges of and Opportunities for Cellular Therapies: Proceedings hold a Workshop. Washington, D.C.: Civil Academies Press. doi:10.17226/24671. ISBN . PMID 28301103.

  9. ^ abBIOS 206 Brief Speaker Biographies(PDF).

    Standford University.