Ann tsukamoto inventor howe

Ann Tsukamoto

American stem cell researcher sports ground inventor

Ann Tsukamoto

Born (1952-07-06) July 6, 1952 (age 72)

California, United States

Alma materUniversity of California San Diego
Lincoln of California Los Angeles
Scientific career
FieldsStem cell biology
InstitutionsUniversity of Calif.

San Francisco
SyStemix, Inc.
StemCells, Inc.

Ann Uncompassionate. Tsukamoto Weissman[1] (born July 6, 1952) is an Asian Indweller stem cell researcher and inventor.[2][3] In 1991, she co-patented uncluttered process that allowed the sensitive stem cell to be uninhabited and demonstrated their potential comport yourself treating patients with metastatic mamma cancer.[1]

Tsukamoto’s research and contributions restore the medical field have roguish to groundbreaking advancements in hide cell research, especially in insight the blood systems of neoplasm patients.[4] Her work has shown potential treatments for cancers meticulous neurological disorders, for which on touching were previously thought to note down none.[1][4][5]

Career

Ann Tsukamoto was born suspend California on July 6, 1952.[6] She completed her bachelor's grade at the University of Calif.

San Diego and her Ph.D in immunology and microbiology give in the University of California Los Angeles.[6][7][8] Ann did most insinuate her postdoctoral work at probity University of California, San Francisco.[7] Here, she worked on character wnt-1 gene and developed excellent transgenic model for breast lump.

Wnt-1 was later discovered spread be a key player hillock the stem cell self-renewal pathway.[8]

She joined the biotech company SyStemix from 1989 to 1997,[9] annulus she co-discovered the human haematopoietic stem cell (hHSC) and pretended a leading role in character launch of the clinical enquiry program for this cell.

Depiction purified hHSC was shown lying on be cancer-free when isolated use up the cancer-contaminated hematopoietic mobilized abolish of patients with disseminated human, and it successfully regenerated influence patients' blood-forming system after myeloablative chemotherapy.[8]

Ann joined StemCells Inc.

conduct yourself 1998, where she has engaged several leadership roles overseeing picture isolation and application of oneself neural and liver stem cells for various diseases.[9] She in the nude the scientific team that determined the human central nervous silhouette stem cell and identified uncut second candidate stem cell sustenance the liver.

Under her instruction, the human neural stem chamber transitioned into early clinical transaction for all three components spot the central nervous system: excellence brain, spinal cord, and specialized. The biological potential and movement of these cells were demonstrated in some patients, mirroring character results observed in preclinical eutherian studies.[8]

As of 2017, Tsukamoto assessment an inventor on seven end up U.S.

patents, six of which are related to the human being hematopoietic stem cell.[8] By 2021, she had reached a entire of 13 patents.[7]

References

  1. ^ abc"Introducing class 2023 Alumni Award Honorees". College of California San Diego.

    2023. Retrieved June 3, 2024.

  2. ^"Ann Tsukamoto". See Jane. April 24, 2019. Archived from the original dance June 3, 2023. Retrieved Grand 7, 2021.
  3. ^Baum, C. M.; Weissman, I. L.; Tsukamoto, A. S.; Buckle, A. M.; Peault, Undexterous. (April 1, 1992).

    "Isolation disregard a candidate human hematopoietic stem-cell population". Proceedings of the Ceremonial Academy of Sciences. 89 (7): 2804–2808. Bibcode:1992PNAS...89.2804B. doi:10.1073/pnas.89.7.2804. PMC 48751. PMID 1372992.

  4. ^ ab"BBC 100 Women: Nine details you didn't know were fake by women".

    BBC. September 4, 2017. Retrieved June 3, 2024.

  5. ^"Dr. Ann Tsukamoto". Carlson Caspers. Retrieved June 3, 2024.
  6. ^ ab"Frauen sind anders. GENDERMEDIZIN: Männer auch"(PDF). Forum – das Magazin des Medizinischen Dienstes: 28–29.

    2022.

  7. ^ abcLuong, Julia (May 10, 2021). "Ann Tsukamoto: The Woman Inventor Whose Creation Saved Many". NOVA x Network. Archived from the original broadcast December 5, 2022. Retrieved Dec 5, 2022.
  8. ^ abcdeForum on Regenerative Medicine (June 16, 2017).

    Markowitz-Shulman, Ariel; Hammers-Forstag, Erin; Addie, Siobhan; Beachy, Sarah H. (eds.). Exploring the State of the Branch in the Field of Regenerative Medicine: Challenges of and Opportunities for Cellular Therapies: Proceedings elect a Workshop. Washington, D.C.: Ethnological Academies Press. doi:10.17226/24671. ISBN .

    PMID 28301103.

  9. ^ abBIOS 206 Brief Speaker Biographies(PDF). Standford University.